Morphological variations of two cases of maxillary myofibromas

The aim of this case report is to depict the varied spectrum clinical presentation two cases solitary myofibromas, one which was intra-osseous whilst other presented as a soft tissue lesion. This highlights same pathology. In most recent World Health Organisation (WHO) 2022 classification tumours, myofibroma included under category myopericytomas. Myopericytoma distinctive perivascular myoid neoplasm that forms morphological with myofibroma. Molecular evidence has revealed PDGFRB (platelet-derived growth factor receptor beta) mutations in myopericytoma and well SRF-RELA gene fusions both lesions confirming common pathogenesis for both.1 Myofibromas are benign neoplasms derived from myofibroblastic cells.2 term refers Myofibromatosis multiple present may affect either or anatomical locations. almost exclusively seen young children age 2-years. exhibit wide range be at birth arise within first years age, but also adults significant male predominance. Solitary myofibromas have predilection occur oral cavity, skin subcutis head, neck trunk.